Services

Stem Cell Models

Unlock Human-Relevant Insights Early

Stem Cell Models

Models

  • iPSC-derived cardiomyocytes, neurons
  • ESC-derived cells
  • Co-culture systems
  • 3D spheroids / organoids

Stem cells provide powerful, physiologically relevant models for drug discovery, toxicity assessment, and disease research. Leveraging stem cell technology allows you to study human biology in vitro, reducing reliance on animal models and improving translational confidence.

ChanPharm offers comprehensive stem cell studies, integrating functional assays, electrophysiology, and 3D tissue modeling to deliver actionable insights for drug discovery and safety evaluation.

What We Offer

Our stem cell services provide human-relevant, mechanistic data to guide early-stage research and lead optimization.

  • Modeling human biology and disease in vitro
  • Evaluating drug effects on cellular physiology and function
  • Supporting toxicity and safety assessment
  • Enabling mechanistic and translational research

Stem Cell Models & Experimental Formats

Cellular Models

  • Human iPSC-derived cardiomyocytes, neurons, and other cell types
  • Co-culture systems for tissue-level interactions

Experimental Formats

  • Single cells
  • Monolayers
  • 2D networks
  • 3D spheroids / microtissues / organoids

These multi-scale formats allow translation from cellular to tissue-level function.

Methods & Data

  • Electrophysiology: action potentials, ion channel currents, excitability
  • Functional Imaging: calcium transients, voltage dynamics
  • Contractility & Mechanical Function (for cardiomyocytes)
  • Network activity & synchrony (neurons or cardiac tissues)

Technologies

Our stem cell studies are supported by industry-standard platforms for electrophysiology, imaging, and 3D tissue modeling.

SyncroPatch 384 / Patchliner (Nanion)

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Automated patch clamp for iPSC-derived cells.
The SyncroPatch 384 and Patchliner enable high-quality electrophysiological recordings from fragile iPSC-derived cardiomyocytes and neurons, supporting both high-throughput screening and detailed characterization of ion channel activity.

Best suited for: Ion channel pharmacology, action potential profiling, drug safety screening

NANION TECHNOLOGIES HIGH THROUGHPUT

MEA Systems (Multi Channel Systems)

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Network-level electrophysiology.
Microelectrode Array (MEA) technology records extracellular field potentials from iPSC-derived cardiomyocyte or neuronal networks, capturing spontaneous activity, drug-induced changes in beat rate, and arrhythmia-like events in a physiological context.

Best suited for: Network activity analysis, cardiotoxicity / neurotoxicity assessment, chronic drug exposure

MCS PHYSIOLOGICAL RELEVANCE

High-Speed sCMOS Imaging (Kinetix)

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High-speed functional imaging.
The Kinetix sCMOS camera enables rapid imaging of calcium transients and voltage dynamics in large cell populations with exceptional temporal resolution, supporting phenotypic analysis across 2D monolayers and 3D tissues.

Best suited for: Calcium handling, voltage dynamics, high-content phenotypic profiling

PHOTOMETRICS HIGH SPEED

3D Microtissue Platforms

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Tissue-level modeling.
3D spheroid and organoid platforms allow iPSC-derived cells to self-organize into architecturally relevant microtissues, enabling studies that better recapitulate in vivo physiology compared to standard 2D cultures.

Best suited for: Disease modeling, toxicity studies in complex tissue environments, translational research

3D MODELS ORGANOIDS

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Applications & Use Cases

Early drug discovery using human-relevant models
Cardiac, neuronal, or hepatic toxicity assessment
Lead optimization and mechanistic exploration
Disease modeling and translational research

Study Workflow

1

Study Design & Endpoint Selection

Define biological questions and experimental endpoints.

2

Platform Selection

Optimize cell type and format for mechanistic insight.

3

Data Analysis and Quality Control

Rigorous experimental execution with reproducible results.

4

Validation of Drug Candidates on Cellular Models

Deliver actionable, decision-ready insights.

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