Functional ion channel assays

ChanPharm offers a large collection of functional ion channel assays for selectivity profiling. Our functional assays utilize automated electrophysiology platforms and manual patch clamp

Safety assessment studies on ion channels

ChanPharm’s safety assessment panel covers key ion channels and enables identification of adverse drug reactions. Profiling against a broad panel of these off-targets at an early stage of drug development supports lead generation, lead optimization and selection of a drug candidate.

Customized cell line generation

Stable cell lines expressing recombinant ion channels are commonly used in drug discovery and safety assessment

Virtual drug screening and drug discovery services

Pharmacophore-based in-silico screening is an efficient and well established method for filtering large virtual compound libraries

ChanPharm is a contract research organisation (CRO) offering compound screening and selectivity profiling for a broad range of ion channels. ChanPharm’s scientists made important contributions to ion channel research for more than 30 years. We are experts in developing ion channel assays that address individual demands of our clients.

Functional ion channel assays

Safety assessment studies on ion channels

Customized cell line generation

Virtual drug screening and drug discovery services